Biophysical Journal Archives - RTG 3120 Biomolecular Condensates https://dresdencondensates.org/tag/biophysical-journal/ From Physics to Biological Functions Mon, 15 Aug 2022 08:20:18 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.1 https://dresdencondensates.org/wp-content/uploads/2022/01/cropped-Icon-32x32.jpg Biophysical Journal Archives - RTG 3120 Biomolecular Condensates https://dresdencondensates.org/tag/biophysical-journal/ 32 32 The key role of solvent in condensation: Mapping water in liquid-liquid phase-separated FUS https://dresdencondensates.org/the-key-role-of-solvent-in-condensation-mapping-water-in-liquid-liquid-phase-separated-fus/ https://dresdencondensates.org/the-key-role-of-solvent-in-condensation-mapping-water-in-liquid-liquid-phase-separated-fus/#respond Tue, 06 Apr 2021 08:09:39 +0000 https://dresdencondensates.org/?p=996 What drives the formation of biomolecular condensates from proteins in water? The Adams group, in collaboration with colleagues from Ruhr-University […]

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]]> What drives the formation of biomolecular condensates from proteins in water? The Adams group, in collaboration with colleagues from Ruhr-University Bochum, Germany, measured the thermodynamic forces leading to the expulsion of water from condensates as they form through protein-protein interactions. the results are published in the Biophysical Journal. Read more.

Scheme showing the proposed water-mediated contribution of FUS to LLPS. Formation of phase-separated droplets is supported by an increase in tetrahedral coordination of water molecules (bound water; thick black) and minimization of less favorable water interactions (wrap water; red).

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