Physical Chemistry – RTG 3120 Biomolecular Condensates https://dresdencondensates.org From Physics to Biological Functions Wed, 04 Mar 2026 10:18:28 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 https://dresdencondensates.org/wp-content/uploads/2022/01/cropped-Icon-32x32.jpg Physical Chemistry – RTG 3120 Biomolecular Condensates https://dresdencondensates.org 32 32 Ellen Adams https://dresdencondensates.org/portfolio/ellen-adams-group/ Mon, 15 Aug 2022 08:22:12 +0000 https://dresdencondensates.org/?post_type=portfolio&p=992
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Portrait from Ellen Adams
© TUD CMCB, Magdalena Gonciarz

Expertise

The Adams group has a strong background in physical chemistry and soft matter physics, utilizing spectroscopic methods. Key research topics include solvation dynamics, specific ion effects, and protein-water interactions1. In recent years, the group has developed spectroscopic methods for probing the solvent environment in biomolecular condensates, which revealed that release of hydration water is an entropic driving force for liquid-liquid phase separation1,2.

References:

  1. Adams et al. Local Mutations Can Serve as a Game Changer for Global Protein Solvent Interaction. JACS Au. 2021;1(7):1076-1085. https://doi.org/10.1021/jacsau.1c00155
  2. Ahlers, Adams et al. The key role of solvent in condensation: Mapping water in liquid-liquid phase-separated FUS. Biophys J. 2021;120(7):1266-1275. https://doi.org/10.1016/j.bpj.2021.01.019

Scheme showing that The stripping away of less favorable hydration water drives the liquid-liquid phase separation
The stripping away of less favorable hydration water drives the liquid-liquid phase separation of intrinsically disordered proteins, leading to a constrained hydration environment within the phase separated condensates

Ellen Adams Group

Physical chemistry of biomolecular condensates

Discipline: Physical Chemistry

Affiliation: Physics of Life (TU Dresden) | Helmholtz Zentrum Dresden Rossendorf (HZDR) | Dresden Concept

Contact: ellen_marie.adams (at) tu-dresden (dot) de

RTG Project: A3

Funding

Current news by this research group

Awards,Simon Alberti Group,Anthony Hyman Group,RTG 3120

Alberti and Hyman among Clarivate’s Highly Cited Researchers in 2025

  RTG 3120 PI's have been among the most highly cited authors in 2025, according to Clarivate, with Hyman and Alberti leading the way "in the top 1% by citations for their field(s) and publication year in the Web of Science Core Collection" See the press release by TU Dresden:…

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RTG 3120

New Research Training Group for Biomolecular Condensates in Dresden

The DFG approved a funding application to establish a new Research Training Group (RTG 3120) in Dresden to train PhD students interdisciplinary methods and approaches to study Biomolecular Condensates. Read the press releases for more:…

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Jan Brugués Group,Programs,careers,Ellen Adams Group,Physics of Life

Physics of Life Excellence Postdoctoral Fellowships

Join research groups at the Physics of Life (PoL) as a postdoc by applying to a PoL Excellence Postdoctoral Fellowship and benefit from up to 4-year funded position in association with PoL groups and the Mentorship program. Applicants should hold a PhD in Physics, Biology or related fields (at the…

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