RTG 3120 Biomolecular Condensates
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20. August 2025

Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

A new study from the labs of Honigmann, Hyman, and Alberti in Dresden, in addition to colleagues in Texas A&M University, Mayo Clinic, Brown University, and Saint Louis University investigates the mechanism behind pathological outcomes of protein aggregation inside stress granules. The authors…

12. January 2022

A role for RNA in Stress Granules assembly

Stress granules are membraneless compartments formed by phase separation of specific molecules upon exposure to cellular stress such as oxidative stress, heat shock, or osmotic stress. The Alberti, Jahnel, Honigmann, and Hyman labs published a study in cell highlighting the role of RNA in the…

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Alf Honigmann Group, Anthony Hyman Group, Publications, Simon Alberti Group

Funding

TUD

Funded by the DFG

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Imprint / Provider Identification – Accessibility – Editor: Mohamad Almedawar (almedawar (at) tu-dresden (dot) de)

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