DateGroupsTitleJournalCommentary 03.01.2021Honigmann, Jülicher Transcription organizes euchromatin via microphase separationNat Comm 11.12.2020Hyman, JülicherProtein condensates as aging Maxwell fluidsScience 03.11.2020AlbertiProtein phase separation and its role in tumorigenesisElife 01.11.2020AlbertiBAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomesCell Stress Chaperones 01.10.2020AlbertiBiomolecular condensates undergo a generic shear-mediated liquid-to-solid transitionNat Nanotechnol 03.09.2020AlbertiThe plant response to heat requires phase separationNature 08.07.2020Alberti, PiginoFilament formation by the translation factor eIF2B regulates protein synthesis in starved cellsBiol Open 02.07.2020AlbertiThe Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress GranulesMol Cell 19.06.2020HymanPartitioning of cancer therapeutics in nuclear condensatesScience 01.06.2020Alberti, PiginoReorganization of budding yeast cytoplasm upon energy depletionMol Biol Cell 27.05.2020Tang High-Throughput Synthesis and Screening of Functional Coacervates Using MicrofluidicsChemSystemsChem 14.05.2020Alberti, Hyman, KreysingCondensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein ProductionCellCondensation regulates translation 16.04.2020Alberti, Guck, Honigmann, Hyman RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by CondensationCell A role for RNA in Stress Granules assembly 06.04.2020Tang Reversible pH-Responsive Coacervate Formation in Lipid Vesicles Activates Dormant Enzymatic ReactionsAngewandte Chemie Int Ed Engl 01.03.2020Alberti ALS and FTD: Where RNA metabolism meets protein quality controlSemin Cell Dev Biol 12.02.2020KreysingRegulated changes in material properties underlie centrosome disassembly during mitotic exitJ Cell Biol 24.01.2020Honigmann, Hyman, Jülicher, ZechnerPhase separation provides a mechanism to reduce noise in cellsScience 09.12.2019KreysingMaterial aging causes centrosome weakening and disassembly during mitotic exitbioRxiv (preprint) 03.12.2019AlbertiLiquid-Liquid Phase Separation in DiseaseAnnu Rev Genet 31.10.2019Honigmann Phase Separation of Zonula Occludens Proteins Drives Formation of Tight JunctionsCell 21.10.2019KreysingProbing the Functional Role of Physical Motion in DevelopmentDevelopmental Cell 21.10.2019Brugués, Hyman, JülicherSoluble tubulin is significantly enriched at mitotic centrosomesJ Cell Biol Enrichment of soluble tubulin at centrosomes 07.10.2019AlbertiNucleolus: A Liquid Droplet Compartment for Misbehaving ProteinsCurr Biol 24.09.2019Alberti Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular CondensatesCell 02.09.2019Diez, HymanKinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymesNat Cell Biol 26.08.2019AlbertiNucleoli and Promyelocytic Leukemia Protein (PML) bodies are phase separated nuclear protein quality control compartments for misfolded proteinsMol Cell Oncol 01.08.2019Alberti Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitinEMBO J 11.07.2019Tang Microfluidic Tools for Bottom-Up Synthetic CellularityChem 02.07.2019AlbertiProteome-wide signatures of function in highly diverged intrinsically disordered regionsElife 13.06.2019Alberti The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivoNat Commun 03.06.2019Alberti Protein Phase Separation as a Stress Survival StrategyCold Spring Harb Perspect Biol 03.05.2019Alberti Prion-like low-complexity sequences: Key regulators of protein solubility and phase behaviorJ Biol Chem 01.04.2019Alberti, HymanFUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagyActa Neuropathologica 01.03.2019Alberti Small heat shock proteins: multifaceted proteins with important implications for lifeCell Stress Chaperones 06.02.2019Hyman, Tang Directed Growth of Biomimetic MicrocompartmentsAdvanced Biosystems 18.12.2018Hyman, JülicherSalt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical TrapsPhysical Review Letters 10.12.2018KreysingAcetylation of intrinsically disordered regions regulates phase separationNat Chem Biol 10.12.2018Hyman Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cellsEMBO J 09.11.2018Hyman PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formationJ Cell Sci 02.11.2018Alberti, Hyman A User's Guide for Phase Separation Assays with Purified ProteinsJ Mol Biol 02.11.2018AlbertiQuality Control of Membraneless OrganellesJ Mol Biol 12.10.2018Hyman, Jülicher Positioning of Particles in Active DropletsPhysical Review Letters 07.09.2018Kreysing, TangCompartmentalised RNA catalysis in membrane-free coacervate protocellsNat Commun 04.09.2018Hyman Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication CompartmentsmBio 10.08.2018Alberti Phase changes in neurotransmissionScience 26.07.2018Alberti, Hyman A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding ProteinsCell 12.06.2018Alberti, HymanDifferent Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery Cell Rep 25.05.2018Alberti, Hyman RNA buffers the phase separation behavior of prion-like RNA binding proteinsScience 11.05.2018Hyman, Tang MaxSynBio: Avenues Towards Creating Cells from the Bottom UpAngewendete Chemie Int Ed Engl 09.04.2018Hyman Controlling compartmentalization by non-membrane-bound organellesPhilos Trans R Soc Lond B Biol Sci 27.03.2018Alberti Protein Phase Separation: A New Phase in Cell BiologyTrends Cell Biol 15.03.2018 Phase shifts in protein folding space: links to stress adaptation and diseaseMol Biol Cell 22.02.2018Hyman Tau protein liquid-liquid phase separation can initiate tau aggregationEMBO J 13.02.2018Alberti, Hyman Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing AutophagyStem Cell Reports 01.02.2018Hyman Organization and Function of Non-dynamic Biomolecular CondensatesTrends Biochem Sci 23.01.2018Grill, Hyman Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formationNat Commun 05.01.2018Alberti, Grill, Hyman Phase separation of a yeast prion protein promotes cellular fitnessScience 02.01.2018Tang Microfluidic formation of proteinosomesChem Commun (Camb) 01.12.2016Tang Polynucleotides in cellular mimics: Coacervates and lipid vesiclesCurrent Opinion in Colloid & Interface Science 21.07.2015Tang In vitro gene expression within membrane-free coacervate protocellsChem Commun (Camb) 27.05.2015Tang Microfluidic Formation of Membrane-Free Aqueous Coacervate Droplets in WaterAngewandte Chemie Int Ed Engl 19.06.2014Tang Synthetic cellularity based on non-lipid micro-compartments and protocell modelsCurr Opin Chem Biol 20.04.2014Tang Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell modelNature Chem 03.07.2013Tang Small-molecule uptake in membrane-free peptide/nucleotide protocellsSoft Matter 01.05.2013AlbertiProtein disorder, prion propensities, and self-organizing macromolecular collectivesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics 10.10.2012Alberti Molecular mechanisms of spatial protein quality controlPrion 01.09.2012Alberti Prion formation by a yeast GLFG nucleoporinPrion 20.06.2012Alberti Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregatesMolecular Biology of the Cell 07.07.2011Alberti Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered ProteinsMolecular Cell 01.09.2010Alberti Prions, protein homeostasis, and phenotypic diversityTrends Cell Biol 01.01.2010Alberti Biochemical, cell biological, and genetic assays to analyze amyloid and prion aggregation in yeastMethods in enzymology
