Current news by our research groups
Felix Mueller-Planitz Group,careers
We’re currently hiring!
We’re looking for Master and PhD students. Get in touch if you love epigenetics, genomics, and long-read sequencing as much as we do! Especially if you have an affinity not only for molecular biology but also for bioinformatics! Students interested in a PhD project should apply to the Dresden…
Alf Honigmann Group,Anthony Hyman Group,Marcus Jahnel Group,Simon Alberti Group
A role for RNA in Stress Granules assembly
Stress granules are membraneless compartments formed by phase separation of specific molecules upon exposure to cellular stress such as oxidative stress, heat shock, or osmotic stress. The Alberti, Jahnel, Honigmann, and Hyman labs published a study in cell highlighting the role of RNA in the…
Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells
Aminoacyl-tRNA synthetases (aaRSs), the enzymes responsible for coupling tRNAs to their cognate amino acids, minimize translational errors by intrinsic hydrolytic editing. Here, we compared norvaline (Nva), a linear amino acid not coded for protein synthesis, to the proteinogenic, branched valine…
Regulated changes in material properties underlie centrosome disassembly during mitotic exit
Aminoacyl-tRNA synthetases (aaRSs), the enzymes responsible for coupling tRNAs to their cognate amino acids, minimize translational errors by intrinsic hydrolytic editing. Here, we compared norvaline (Nva), a linear amino acid not coded for protein synthesis, to the proteinogenic, branched valine…
Simon Alberti Group,Anthony Hyman Group,Moritz Kreysing Group
Condensation regulates translation
New insights into the influence of Ded1p condensation on translation comes from the Hyman, Alberti and Kreysing labs. The study published in Cell is entitled "Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production". Graphical abstract: Abstract: Cells…
Learn the basics of Biomolecuar Condensates
Go to the Science Sketches page for more cool explanatory movies.