2022Grill, Jülicher A condensate dynamic instability orchestrates actomyosin cortex activationNature
2022Jülicher Chemical Kinetics and Mass Action in Coexisting PhasesJ Am Chem Soc
2021Alberti Quantitative proteomics identifies the universally conserved ATPase Ola1p as a positive regulator of heat shock response in Saccharomyces cerevisiaeJ Biol Chem
2021Alberti Adaptable P body physical states differentially regulate bicoid mRNA storage during early Drosophila developmentDev Cell
2022Alberti, Jahnel Surface Electrostatics Govern the Emulsion Stability of Biomolecular CondensatesNano Lett
2022Alberti Correlative all-optical quantification of mass density and mechanics of subcellular compartments with fluorescence specificityElife
2022Alberti CAPRIN1P512L causes aberrant protein aggregation and associates with early-onset ataxiaCellular and Molecular Life Sciences
2022Alberti, Hyman Biomolecular condensate phase diagrams with a combinatorial microdroplet platformNat Comm
2022Alberti Cytosolic stress granules relieve the ubiquitin-proteasome system in the nuclear compartment EMBO J
2022Alberti, Hyman Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutionsPNAS
2022Alberti, HymanSAMHD1 controls innate immunity by regulating condensation of immunogenic self RNAMol Cell
2021Honigmann, Jülicher Transcription organizes euchromatin via microphase separationNat Comm
2021Diez The ALS-Associated FUS (P525L) Variant Does Not Directly Interfere with Microtubule-Dependent Kinesin-1 MotilityInt. J. Mol. Sci.
2020Alberti ALS and FTD: Where RNA metabolism meets protein quality controlSemin Cell Dev Biol
2020Alberti, PiginoReorganization of budding yeast cytoplasm upon energy depletionMol Biol Cell
2020AlbertiBiomolecular condensates undergo a generic shear-mediated liquid-to-solid transitionNat Nanotechnol
2020AlbertiBAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomesCell Stress Chaperones
2020AlbertiThe Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress GranulesMol Cell
2020AlbertiThe plant response to heat requires phase separationNature
2020AlbertiProtein phase separation and its role in tumorigenesisElife
2020Tang Reversible pH-Responsive Coacervate Formation in Lipid Vesicles Activates Dormant Enzymatic ReactionsAngewandte Chemie Int Ed Engl
2020Alberti, PiginoFilament formation by the translation factor eIF2B regulates protein synthesis in starved cellsBiol Open
2020Hyman, JülicherProtein condensates as aging Maxwell fluidsScience
2020KreysingRegulated changes in material properties underlie centrosome disassembly during mitotic exitJ Cell Biol
2020Alberti, Hyman, KreysingCondensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein ProductionCell
2020Diez Cytoskeletal organization through multivalent interactionsJ Cell Sci
2020Alberti, Guck, Honigmann, Hyman RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by CondensationCell
2020HymanPartitioning of cancer therapeutics in nuclear condensatesScience
2020Honigmann, Hyman, Jülicher, ZechnerPhase separation provides a mechanism to reduce noise in cellsScience
2020Tang High-Throughput Synthesis and Screening of Functional Coacervates Using MicrofluidicsChemSystemsChem
2019Alberti Small heat shock proteins: multifaceted proteins with important implications for lifeCell Stress Chaperones
2019Alberti, HymanFUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagyActa Neuropathologica
2019Alberti Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitinEMBO J
2019AlbertiProteome-wide signatures of function in highly diverged intrinsically disordered regionsElife
2019Diez, HymanKinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymesNat Cell Biol
2019Alberti Prion-like low-complexity sequences: Key regulators of protein solubility and phase behaviorJ Biol Chem
2019Alberti Protein Phase Separation as a Stress Survival StrategyCold Spring Harb Perspect Biol
2019AlbertiLiquid-Liquid Phase Separation in DiseaseAnnu Rev Genet
2019Hyman, Tang Directed Growth of Biomimetic MicrocompartmentsAdvanced Biosystems
2019AlbertiNucleolus: A Liquid Droplet Compartment for Misbehaving ProteinsCurr Biol
2019KreysingMaterial aging causes centrosome weakening and disassembly during mitotic exitbioRxiv (preprint)
2019Tang Microfluidic Tools for Bottom-Up Synthetic CellularityChem
2019Alberti The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivoNat Commun
2019Brugués, Hyman, JülicherSoluble tubulin is significantly enriched at mitotic centrosomesJ Cell Biol
2019KreysingProbing the Functional Role of Physical Motion in DevelopmentDevelopmental Cell
2019Alberti Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular CondensatesCell
2019AlbertiNucleoli and Promyelocytic Leukemia Protein (PML) bodies are phase separated nuclear protein quality control compartments for misfolded proteinsMol Cell Oncol
2019Honigmann Phase Separation of Zonula Occludens Proteins Drives Formation of Tight JunctionsCell
2018Hyman Organization and Function of Non-dynamic Biomolecular CondensatesTrends Biochem Sci
2018Tang Microfluidic formation of proteinosomesChem Commun (Camb)
2018AlbertiQuality Control of Membraneless OrganellesJ Mol Biol
2018Alberti, Hyman A User's Guide for Phase Separation Assays with Purified ProteinsJ Mol Biol
2018Hyman Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication CompartmentsmBio
2018Alberti, Grill, Hyman Phase separation of a yeast prion protein promotes cellular fitnessScience
2018Kreysing, TangCompartmentalised RNA catalysis in membrane-free coacervate protocellsNat Commun
2018Hyman Controlling compartmentalization by non-membrane-bound organellesPhilos Trans R Soc Lond B Biol Sci
2018Hyman PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formationJ Cell Sci
2018Alberti Phase changes in neurotransmissionScience
2018Hyman Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cellsEMBO J
2018KreysingAcetylation of intrinsically disordered regions regulates phase separationNat Chem Biol
2018Hyman, Tang MaxSynBio: Avenues Towards Creating Cells from the Bottom UpAngewendete Chemie Int Ed Engl
2018Alberti, HymanDifferent Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery Cell Rep
2018Hyman, Jülicher Positioning of Particles in Active DropletsPhysical Review Letters
2018Alberti, Hyman Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing AutophagyStem Cell Reports
2018Alberti Phase shifts in protein folding space: links to stress adaptation and diseaseMol Biol Cell
2018Hyman, JülicherSalt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical TrapsPhysical Review Letters
2018Hyman Tau protein liquid-liquid phase separation can initiate tau aggregationEMBO J
2018Grill, Hyman Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formationNat Commun
2018Alberti, Hyman RNA buffers the phase separation behavior of prion-like RNA binding proteinsScience
2018Alberti, Hyman A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding ProteinsCell
2018Alberti Protein Phase Separation: A New Phase in Cell BiologyTrends Cell Biol
2018HymanOrganization and Function of Non-dynamic Biomolecular CondensatesTrends Biochem Sci
2017HymanBiomolecular condensates: organizers of cellular biochemistryNat Rev Mol Cell Biol
2017Hyman, AlbertiATP as a biological hydrotropeScience
2017Hyman, HonigmannThe Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating TubulinCell
2017Hyman, AlbertiAn aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone functionEMBO J
2017HymanRNA gets in phaseJ Cell Biol
2017Hyman, Alberti, DiezLocal Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau PhaseCell Rep
2017Hyman, Alberti, GrillPhase separation of a yeast prion protein promotes cellular fitnessScience
2016Tang Polynucleotides in cellular mimics: Coacervates and lipid vesiclesCurrent Opinion in Colloid & Interface Science
2016HymanKi-67 acts as a biological surfactant to disperse mitotic chromosomesNature
2016Hyman, AlbertiAmyloid-like Self-Assembly of a Cellular CompartmentCell
2016Hyman, JülicherPolar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition MechanismCell
2016Hyman, AlbertiAre aberrant phase transitions a driver of cellular aging?Bioessays
2015Tang Microfluidic Formation of Membrane-Free Aqueous Coacervate Droplets in WaterAngewandte Chemie Int Ed Engl
2015Tang In vitro gene expression within membrane-free coacervate protocellsChem Commun (Camb)
2015HymanCentrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitroScience
2015Hyman, JülicherSuppression of Ostwald ripening in active emulsionsPhys Rev E
2015Alberti, Hyman, Grill, Jülicher,A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease MutationCell
2014Tang Synthetic cellularity based on non-lipid micro-compartments and protocell modelsCurr Opin Chem Biol
2014Tang Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell modelNature Chem
2014Hyman, JülicherLiquid-liquid phase separation in biologyAnnu Rev Cellbio
2013AlbertiProtein disorder, prion propensities, and self-organizing macromolecular collectivesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics
2013Tang Small-molecule uptake in membrane-free peptide/nucleotide protocellsSoft Matter
2012Alberti Prion formation by a yeast GLFG nucleoporinPrion
2012Alberti Molecular mechanisms of spatial protein quality controlPrion
2012Alberti Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregatesMolecular Biology of the Cell
2012HymanACell biology. Beyond oil and water--phase transitions in cellsScience
2011Alberti Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered ProteinsMolecular Cell
2011HymanBeyond stereospecificity: liquids and mesoscale organization of cytoplasmDevelopmental Cell
2011HymanActive liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytesPNAS
2010Alberti Biochemical, cell biological, and genetic assays to analyze amyloid and prion aggregation in yeastMethods in enzymology
2010Alberti Prions, protein homeostasis, and phenotypic diversityTrends Cell Biol
2009Hyman, JülicherGermline P granules are liquid droplets that localize by controlled dissolution/condensationScience