TitleAuthorsJournal/BookDOI
Biomolecular condensates sustain pH gradients at equilibrium through charge neutralizationAusserwöger H, Scrutton R, Fischer CM, Sneideris T, Qian D, de Csilléry E, Baronaite I, Saar KL, Białek AZ, Oeller M, Krainer G, Franzmann TM, Wittmann S, Iglesias-Artola JM, Invernizzi G, Hyman AA, Alberti S, Lorenzen N, Knowles TPJ.Nat Chem10.1038/s41557-025-02039-9
A Self-Organized Liquid Reaction Container for Cellular MemoryMukherjee S, Skoruppa E, Merlitz H, Sommer JU, Schiessel H.Adv Sci (Weinh)10.1002/advs.202512500
CD-CODE 2.0: an enhanced condensate knowledgebase integrating pathobiology, condensate modulating drugs, and host-pathogen interactionsKuznetsova K, Scheremetjew M, Yin J, Moon H, Vargas DA, Hadarovich A, Lewis N, Hoege C, Chow CFW, Kuster D, Nijssen J, Hernandez-Armendariz A, Savage JC, Wei Y, Zedlitz S, Singh HR, Ghosh S, Kemraj AP, Hersemann L, Hyman AA, Mitrea DM, Toth-Petroczy A.Nucleic Acids Res10.1093/nar/gkaf1104
TitleAuthorsJournal/BookDOI
RNA-peptide interactions tune the ribozyme activity within coacervate microdroplet dispersionsGhosh B, McCall PM, Le Vay KK, Ghosh A, Hubatsch L, Gonzales DT, Brugués J, Mutschler H, Dora Tang TY.Nat Communhttps://doi.org/10.1038/s41467-025-63656-z
Molecular dynamics investigation of polymer-decorated nanoparticles with co-nonsolvent: Structural transitions from isotropic layers to heterogeneous patches.Li CW, Merlitz H, Sommer JU J Chem Physhttps://doi.org/10.1063/5.0295227
SUMO2/3 conjugation of TDP-43 protects against aggregationVerde EM, Antoniani F, Mediani L, Secco V, Crotti S, Ferrara MC, Vinet J, Sergeeva A, Yan X, Hoege C, Stuani C, Paron F, Kao TT, Shrivastava R, Polanowska J, Bailly A, Rosa A, Aronica E, Goswami A, Shneider N, Hyman AA, Buratti E, Xirodimas D, Franzmann TM, Alberti S, Carra S.Sci Advhttps://doi.org/10.1126/sciadv.adq2475
G3BP-driven RNP granules promote inhibitory RNA-RNA interactions resolved by DDX3X to regulate mRNA translatabilityTrussina IREA, Hartmann A, Desroches Altamirano C, Natarajan J, Fischer CM, Aleksejczuk M, Ausserwöger H, Knowles TPJ, Schlierf M, Franzmann TM, Alberti S.Mol Cellhttps://doi.org/10.1016/j.molcel.2024.11.039
Small-molecule dissolution of stress granules by redox modulation benefits ALS modelsUechi H, Sridharan S, Nijssen J, Bilstein J, Iglesias-Artola JM, Kishigami S, Casablancas-Antras V, Poser I, Martinez EJ, Boczek E, Wagner M, Tomschke N, de Jesus Domingues AM, Pal A, Doeleman T, Kour S, Anderson EN, Stein F, Lee HO, Zhang X, Fritsch AW, Jahnel M, Fürsch J, Murthy AC, Alberti S, Bickle M, Fawzi NL, Nadler A, David DC, Pandey UB, Hermann A, Stengel F, Davis BG, Baldwin AJ, Savitski MM, Hyman AA, Wheeler RJ.Nat Chem Biolhttps://doi.org/10.1038/s41589-025-01893-5
Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregatesYan X, Kuster D, Mohanty P, Nijssen J, Pombo-García K, Garcia Morato J, Rizuan A, Franzmann TM, Sergeeva A, Ly AM, Liu F, Passos PM, George L, Wang SH, Shenoy J, Danielson HL, Ozguney B, Honigmann A, Ayala YM, Fawzi NL, Dickson DW, Rossoll W, Mittal J, Alberti S, Hyman AA.Cellhttps://doi.org/10.1016/j.cell.2025.04.039
Assembly of tight junction belts by ZO1 surface condensation and local actin polymerizationSun D, Zhao X, Wiegand T, Martin-Lemaitre C, Borianne T, Kleinschmidt L, Grill SW, Hyman AA, Weber C, Honigmann A.Dev Cellhttps://doi.org/10.1016/j.devcel.2024.12.012
Impact of Coiled-Coil Domains on the Phase Behavior of Biomolecular CondensatesHe Z, Sommer JU, Harmon TS.ACS Macro Letthttps://doi.org/10.1021/acsmacrolett.4c00821
SHARK-capture identifies functional motifs in intrinsically disordered protein regionsChow CFW, Lenz S, Scheremetjew M, Ghosh S, Richter D, Jegers C, von Appen A, Alberti S, Toth-Petroczy A.Protein Scihttps://doi.org/10.1002/pro.70091
TitleAuthorsJournal/BookDOI
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA endsChappidi N, Quail T, Doll S, Vogel LT, Aleksandrov R, Felekyan S, Kühnemuth R, Stoynov S, Seidel CAM, Brugués J, Jahnel M, Franzmann TM, Alberti S.Cellhttps://doi.org/10.1016/j.cell.2024.01.015
Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregatesYan X, Kuster D, Mohanty P, Nijssen J, Pombo-García K, Rizuan A, Franzmann TM, Sergeeva A, Passos PM, George L, Wang SH, Shenoy J, Danielson HL, Honigmann A, Ayala YM, Fawzi NL, Mittal J, Alberti S, Hyman AA.bioRxivhttps://doi.org/10.1101/2024.01.23.576837
Glycolic acid and D-lactate-putative products of DJ-1-restore neurodegeneration in FUS - and SOD1-ALSPal A, Grossmann D, Glaß H, Zimyanin V, Günther R, Catinozzi M, Boeckers TM, Sterneckert J, Storkebaum E, Petri S, Wegner F, Grill SW, Pan-Montojo F, Hermann A.Life Sci Alliancehttps://doi.org/10.26508/lsa.202302535
eIF4F is a thermo-sensing regulatory node in the translational heat shock responseDesroches Altamirano C, Kang MK, Jordan MA, Borianne T, Dilmen I, Gnädig M, von Appen A, Honigmann A, Franzmann TM, Alberti S.Mol Cellhttps://doi.org/10.1016/j.molcel.2024.02.038
Droplet Differentiation by a Chemical SwitchChen X, Seyboldt R, Sommer JU, Jülicher F, Harmon T.Phys Rev Letthttps://doi.org/10.1103/PhysRevLett.133.028402
PICNIC accurately predicts condensate-forming proteins regardless of their structural disorder across organismsHadarovich A, Singh HR, Ghosh S, Scheremetjew M, Rostam N, Hyman AA, Toth-Petroczy A.Nat Communhttps://doi.org/10.1038/s41467-024-55089-x
Actin polymerization counteracts prewetting of N-WASP on supported lipid bilayersWiegand T, Liu J, Vogeley L, LuValle-Burke I, Geisler J, Fritsch AW, Hyman AA, Grill SW.Proc Natl Acad Sci U S Ahttps://doi.org/10.1073/pnas.2407497121
A self-organised liquid reaction container for cellular memory S Mukherjee, E Skoruppa, H Merlitz, JU Sommer, H SchiesselarXivhttps://doi.org/10.48550/arXiv.2412.15394
TitleAuthorsJournal/BookPublication YearDOI
Publisher Correction: A condensate dynamic instability orchestrates actomyosin cortex activationYan VT, Narayanan A, Wiegand T, Jülicher F, Grill SW.Nature2023https://doi.org/10.1038/s41586-023-05932-w
Topological morphogenesis of neuroepithelial organoidsIshihara K, Mukherjee A, Gromberg E, Brugués J, Tanaka EM, Jülicher F.Nat Phys2023https://doi.org/10.1038/s41567-022-01822-6
CD-CODE: crowdsourcing condensate database and encyclopediaRostam N, Ghosh S, Chow CFW, Hadarovich A, Landerer C, Ghosh R, Moon H, Hersemann L, Mitrea DM, Klein IA, Hyman AA, Toth-Petroczy A.Nat Methods2023https://doi.org/10.1038/s41592-023-01831-0
A condensate dynamic instability orchestrates actomyosin cortex activationYan VT, Narayanan A, Wiegand T, Jülicher F, Grill SW.Nature2022https://doi.org/10.1038/s41586-022-05084-3
Molecular Assembly Lines in Active DropletsHarmon TS, Jülicher F.Phys Rev Lett2022https://doi.org/10.1103/PhysRevLett.128.108102
Co-condensation of proteins with single- and double-stranded DNARenger R, Morin JA, Lemaitre R, Ruer-Gruss M, Jülicher F, Hermann A, Grill SW.Proc Natl Acad Sci U S A2022https://doi.org/10.1073/pnas.2107871119
Surface Electrostatics Govern the Emulsion Stability of Biomolecular CondensatesWelsh TJ, Krainer G, Espinosa JR, Joseph JA, Sridhar A, Jahnel M, Arter WE, Saar KL, Alberti S, Collepardo-Guevara R, Knowles TPJ.Nano Lett2022https://doi.org/10.1021/acs.nanolett.1c03138
Biomolecular condensate phase diagrams with a combinatorial microdroplet platformArter WE, Qi R, Erkamp NA, Krainer G, Didi K, Welsh TJ, Acker J, Nixon-Abell J, Qamar S, Guillén-Boixet J, Franzmann TM, Kuster D, Hyman AA, Borodavka A, George-Hyslop PS, Alberti S, Knowles TPJ.Nat Commun2022https://doi.org/10.1038/s41467-022-35265-7
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutionsKar M, Dar F, Welsh TJ, Vogel LT, Kühnemuth R, Majumdar A, Krainer G, Franzmann TM, Alberti S, Seidel CAM, Knowles TPJ, Hyman AA, Pappu RV.Proc Natl Acad Sci U S A2022https://doi.org/10.1073/pnas.2202222119
SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNAMaharana S, Kretschmer S, Hunger S, Yan X, Kuster D, Traikov S, Zillinger T, Gentzel M, Elangovan S, Dasgupta P, Chappidi N, Lucas N, Maser KI, Maatz H, Rapp A, Marchand V, Chang YT, Motorin Y, Hubner N, Hartmann G, Hyman AA, Alberti S, Lee-Kirsch MA.Mol Cell2022https://doi.org/10.1016/j.molcel.2022.08.031
Polymer-assisted condensation: A mechanism for hetero-chromatin formation and epigenetic memorySommer JU, Merlitz H, Schiessel HMacromolecules2022https://doi.org/10.1021/acs.macromol.2c00244
A hydraulic instability drives the cell death decision in the nematode germlineChartier NT, Mukherjee A, Pfanzelter J, Fürthauer S, Larson BT, Fritsch AW, Amini R, Kreysing M, Jülicher F, Grill SW.Nat Phys2021https://doi.org/10.1038/s41567-021-01235-x
Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensatesFritsch AW, Diaz-Delgadillo AF, Adame-Arana O, Hoege C, Mittasch M, Kreysing M, Leaver M, Hyman AA, Jülicher F, Weber CA.Proc Natl Acad Sci U S A2021https://doi.org/10.1073/pnas.2102772118
Author Correction: Transcription organizes euchromatin via microphase separationHilbert L, Sato Y, Kuznetsova K, Bianucci T, Kimura H, Jülicher F, Honigmann A, Zaburdaev V, Vastenhouw NL.Nat Commun2021https://doi.org/10.1038/s41467-021-24517-7
Transcription organizes euchromatin via microphase separationHilbert L, Sato Y, Kuznetsova K, Bianucci T, Kimura H, Jülicher F, Honigmann A, Zaburdaev V, Vastenhouw NL.Nat Commun2021https://doi.org/10.1038/s41467-021-21589-3
Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageingAlberti S, Hyman AA.Nat Rev Mol Cell Biol2021https://doi.org/10.1038/s41580-020-00326-6
Adaptable P body physical states differentially regulate bicoid mRNA storage during early Drosophila developmentSankaranarayanan M, Emenecker RJ, Wilby EL, Jahnel M, Trussina IREA, Wayland M, Alberti S, Holehouse AS, Weil TT.Dev Cell2021https://doi.org/10.1016/j.devcel.2021.09.021
Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signalingMediani L, Antoniani F, Galli V, Vinet J, Carrà AD, Bigi I, Tripathy V, Tiago T, Cimino M, Leo G, Amen T, Kaganovich D, Cereda C, Pansarasa O, Mandrioli J, Tripathi P, Troost D, Aronica E, Buchner J, Goswami A, Sterneckert J, Alberti S, Carra S.EMBO Rep2021https://doi.org/10.15252/embr.202051740
Thermal fluctuations assist mechanical signal propagation in coiled-coil proteinsClopés J, Shin J, Jahnel M, Grill SW, Zaburdaev V.Phys Rev E2021https://doi.org/10.1103/PhysRevE.104.054403
HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domainBoczek EE, Fürsch J, Niedermeier ML, Jawerth L, Jahnel M, Ruer-Gruß M, Kammer KM, Heid P, Mediani L, Wang J, Yan X, Pozniakovski A, Poser I, Mateju D, Hubatsch L, Carra S, Alberti S, Hyman AA, Stengel F.Elife2021https://doi.org/10.7554/eLife.69377
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactionsKrainer G, Welsh TJ, Joseph JA, Espinosa JR, Wittmann S, de Csilléry E, Sridhar A, Toprakcioglu Z, Gudiškytė G, Czekalska MA, Arter WE, Guillén-Boixet J, Franzmann TM, Qamar S, George-Hyslop PS, Hyman AA, Collepardo-Guevara R, Alberti S, Knowles TPJ.Nat Commun2021https://doi.org/10.1038/s41467-021-21181-9
RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by CondensationGuillén-Boixet J, Kopach A, Holehouse AS, Wittmann S, Jahnel M, Schlüßler R, Kim K, Trussina IREA, Wang J, Mateju D, Poser I, Maharana S, Ruer-Gruß M, Richter D, Zhang X, Chang YT, Guck J, Honigmann A, Mahamid J, Hyman AA, Pappu RV, Alberti S, Franzmann TM.Cell2020https://doi.org/10.1016/j.cell.2020.03.049
Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein ProductionIserman C, Desroches Altamirano C, Jegers C, Friedrich U, Zarin T, Fritsch AW, Mittasch M, Domingues A, Hersemann L, Jahnel M, Richter D, Guenther UP, Hentze MW, Moses AM, Hyman AA, Kramer G, Kreysing M, Franzmann TM, Alberti S.Cell2020https://doi.org/10.1016/j.cell.2020.04.009
Protein condensates as aging Maxwell fluidsJawerth L, Fischer-Friedrich E, Saha S, Wang J, Franzmann T, Zhang X, Sachweh J, Ruer M, Ijavi M, Saha S, Mahamid J, Hyman AA, Jülicher F.Science2020https://doi.org/10.1126/science.aaw4951
Active forces shape the metaphase spindle through a mechanical instabilityOriola D, Jülicher F, Brugués J.Proc Natl Acad Sci U S A2020https://doi.org/10.1073/pnas.2002446117
Erratum: Salt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical Traps [Phys. Rev. Lett. 121, 258101 (2018)]Jawerth LM, Ijavi M, Ruer M, Saha S, Jahnel M, Hyman AA, Jülicher F, Fischer-Friedrich E.Phys Rev Lett2020https://doi.org/10.1103/PhysRevLett.125.229901
Soluble tubulin is significantly enriched at mitotic centrosomesBaumgart J, Kirchner M, Redemann S, Bond A, Woodruff J, Verbavatz JM, Jülicher F, Müller-Reichert T, Hyman AA, Brugués J.J Cell Biol2019https://doi.org/10.1083/jcb.201902069
Guiding self-organized pattern formation in cell polarity establishmentGross P, Kumar KV, Goehring NW, Bois JS, Hoege C, Jülicher F, Grill SW.Nat Phys2019https://doi.org/10.1038/s41567-018-0358-7
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagyMarrone L, Drexler HCA, Wang J, Tripathi P, Distler T, Heisterkamp P, Anderson EN, Kour S, Moraiti A, Maharana S, Bhatnagar R, Belgard TG, Tripathy V, Kalmbach N, Hosseinzadeh Z, Crippa V, Abo-Rady M, Wegner F, Poletti A, Troost D, Aronica E, Busskamp V, Weis J, Pandey UB, Hyman AA, Alberti S, Goswami A, Sterneckert J.Acta Neuropathol2019https://doi.org/10.1007/s00401-019-01998-x
Positioning of Particles in Active DropletsZwicker D, Baumgart J, Redemann S, Müller-Reichert T, Hyman AA, Jülicher F.Phys Rev Lett2018https://doi.org/10.1103/PhysRevLett.121.158102
Morphogenetic degeneracies in the actomyosin cortexNaganathan SR, Fürthauer S, Rodriguez J, Fievet BT, Jülicher F, Ahringer J, Cannistraci CV, Grill SW.Elife2018https://doi.org/10.7554/eLife.37677
Hydrodynamic theory of active matterJülicher F, Grill SW, Salbreux G.Rep Prog Phys2018https://doi.org/10.1088/1361-6633/aab6bb
A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding ProteinsWang J, Choi JM, Holehouse AS, Lee HO, Zhang X, Jahnel M, Maharana S, Lemaitre R, Pozniakovsky A, Drechsel D, Poser I, Pappu RV, Alberti S, Hyman AA.Cell2018https://doi.org/10.1016/j.cell.2018.06.006
A User's Guide for Phase Separation Assays with Purified ProteinsAlberti S, Saha S, Woodruff JB, Franzmann TM, Wang J, Hyman AA.J Mol Biol2018https://doi.org/10.1016/j.jmb.2018.06.038
RNA buffers the phase separation behavior of prion-like RNA binding proteinsMaharana S, Wang J, Papadopoulos DK, Richter D, Pozniakovsky A, Poser I, Bickle M, Rizk S, Guillén-Boixet J, Franzmann TM, Jahnel M, Marrone L, Chang YT, Sterneckert J, Tomancak P, Hyman AA, Alberti S.Science2018https://doi.org/10.1126/science.aar7366
Protein Dynamics in Complex DNA LesionsAleksandrov R, Dotchev A, Poser I, Krastev D, Georgiev G, Panova G, Babukov Y, Danovski G, Dyankova T, Hubatsch L, Ivanova A, Atemin A, Nedelcheva-Veleva MN, Hasse S, Sarov M, Buchholz F, Hyman AA, Grill SW, Stoynov SS.Mol Cell2018https://doi.org/10.1016/j.molcel.2018.02.016
Phase separation of a yeast prion protein promotes cellular fitnessFranzmann TM, Jahnel M, Pozniakovsky A, Mahamid J, Holehouse AS, Nüske E, Richter D, Baumeister W, Grill SW, Pappu RV, Hyman AA, Alberti S.Science2018https://doi.org/10.1126/science.aao5654
Non-invasive perturbations of intracellular flow reveal physical principles of cell organizationMittasch M, Gross P, Nestler M, Fritsch AW, Iserman C, Kar M, Munder M, Voigt A, Alberti S, Grill SW, Kreysing M.Nat Cell Biol2018https://doi.org/10.1038/s41556-017-0032-9
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing AutophagyMarrone L, Poser I, Casci I, Japtok J, Reinhardt P, Janosch A, Andree C, Lee HO, Moebius C, Koerner E, Reinhardt L, Cicardi ME, Hackmann K, Klink B, Poletti A, Alberti S, Bickle M, Hermann A, Pandey UB, Hyman AA, Sterneckert JL.Stem Cell Reports2018https://doi.org/10.1016/j.stemcr.2017.12.018
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formationNaumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, Jin M, Stanslowsky N, Reinhardt P, Sterneckert J, Frickenhaus M, Pan-Montojo F, Storkebaum E, Poser I, Freischmidt A, Weishaupt JH, Holzmann K, Troost D, Ludolph AC, Boeckers TM, Liebau S, Petri S, Cordes N, Hyman AA, Wegner F, Grill SW, Weis J, Storch A, Hermann A.Nat Commun2018https://doi.org/10.1038/s41467-017-02299-1
Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and RecoveryKroschwald S, Munder MC, Maharana S, Franzmann TM, Richter D, Ruer M, Hyman AA, Alberti S.Cell Rep2018https://doi.org/10.1016/j.celrep.2018.05.041
Salt-Dependent Rheology and Surface Tension of Protein Condensates Using Optical TrapsJawerth LM, Ijavi M, Ruer M, Saha S, Jahnel M, Hyman AA, Jülicher F, Fischer-Friedrich E.Phys Rev Lett2018https://doi.org/10.1103/PhysRevLett.121.258101
Correction: Controlling contractile instabilities in the actomyosin cortexNishikawa M, Naganathan SR, Jülicher F, Grill SW.Elife2017https://doi.org/10.7554/eLife.30537
Controlling contractile instabilities in the actomyosin cortexNishikawa M, Naganathan SR, Jülicher F, Grill SW.Elife2017https://doi.org/10.7554/eLife.19595
ATP as a biological hydrotropePatel A, Malinovska L, Saha S, Wang J, Alberti S, Krishnan Y, Hyman AA.Science2017https://doi.org/10.1126/science.aaf6846
Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau PhaseHernández-Vega A, Braun M, Scharrel L, Jahnel M, Wegmann S, Hyman BT, Alberti S, Diez S, Hyman AA.Cell Rep2017https://doi.org/10.1016/j.celrep.2017.08.042
The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating TubulinWoodruff JB, Ferreira Gomes B, Widlund PO, Mahamid J, Honigmann A, Hyman AA.Cell2017https://doi.org/10.1016/j.cell.2017.05.028
An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone functionMateju D, Franzmann TM, Patel A, Kopach A, Boczek EE, Maharana S, Lee HO, Carra S, Hyman AA, Alberti S.EMBO J2017https://doi.org/10.15252/embj.201695957
Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformationWueseke O, Zwicker D, Schwager A, Wong YL, Oegema K, Jülicher F, Hyman AA, Woodruff JB.Biol Open2016https://doi.org/10.1242/bio.020990
Rheology of the Active Cell Cortex in MitosisFischer-Friedrich E, Toyoda Y, Cattin CJ, Müller DJ, Hyman AA, Jülicher F.Biophys J2016https://doi.org/10.1016/j.bpj.2016.06.008
Mechanisms of backtrack recovery by RNA polymerases I and IILisica A, Engel C, Jahnel M, Roldán É, Galburt EA, Cramer P, Grill SW.Proc Natl Acad Sci U S A2016https://doi.org/10.1073/pnas.1517011113
An endosomal tether undergoes an entropic collapse to bring vesicles togetherMurray DH, Jahnel M, Lauer J, Avellaneda MJ, Brouilly N, Cezanne A, Morales-Navarrete H, Perini ED, Ferguson C, Lupas AN, Kalaidzidis Y, Parton RG, Grill SW, Zerial M.Nature2016https://doi.org/10.1038/nature19326
Amyloid-like Self-Assembly of a Cellular CompartmentBoke E, Ruer M, Wühr M, Coughlin M, Lemaitre R, Gygi SP, Alberti S, Drechsel D, Hyman AA, Mitchison TJ.Cell2016https://doi.org/10.1016/j.cell.2016.06.051
Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition MechanismSaha S, Weber CA, Nousch M, Adame-Arana O, Hoege C, Hein MY, Osborne-Nishimura E, Mahamid J, Jahnel M, Jawerth L, Pozniakovski A, Eckmann CR, Jülicher F, Hyman AA.Cell2016https://doi.org/10.1016/j.cell.2016.08.006
Are aberrant phase transitions a driver of cellular aging?Alberti S, Hyman AA.Bioessays2016https://doi.org/10.1002/bies.201600042
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease MutationPatel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S.Cell2015https://doi.org/10.1016/j.cell.2015.07.047
Temperature Dependence of Cell Division Timing Accounts for a Shift in the Thermal Limits of C. elegans and C. briggsaeBegasse ML, Leaver M, Vazquez F, Grill SW, Hyman AA.Cell Rep2015https://doi.org/10.1016/j.celrep.2015.01.006
Suppression of Ostwald ripening in active emulsionsZwicker D, Hyman AA, Jülicher F.Phys Rev E Stat Nonlin Soft Matter Phys2015https://doi.org/10.1103/PhysRevE.92.012317
Active torque generation by the actomyosin cell cortex drives left-right symmetry breakingNaganathan SR, Fürthauer S, Nishikawa M, Jülicher F, Grill SW.Elife2014https://doi.org/10.7554/eLife.04165
Liquid-liquid phase separation in biologyHyman AA, Weber CA, Jülicher F.Annu Rev Cell Dev Biol2014https://doi.org/10.1146/annurev-cellbio-100913-013325
Quantification of surface tension and internal pressure generated by single mitotic cellsFischer-Friedrich E, Hyman AA, Jülicher F, Müller DJ, Helenius J.Sci Rep2014https://doi.org/10.1038/srep06213
Centrosomes are autocatalytic droplets of pericentriolar material organized by centriolesZwicker D, Decker M, Jaensch S, Hyman AA, Jülicher F.Proc Natl Acad Sci U S A2014https://doi.org/10.1073/pnas.1404855111
Spatial organization of the cell cytoplasm by position-dependent phase separationLee CF, Brangwynne CP, Gharakhani J, Hyman AA, Jülicher F.Phys Rev Lett2013https://doi.org/10.1103/PhysRevLett.111.088101
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubulesReber SB, Baumgart J, Widlund PO, Pozniakovsky A, Howard J, Hyman AA, Jülicher F.Nat Cell Biol2013https://doi.org/10.1038/ncb2834
Pattern formation in active fluidsBois JS, Jülicher F, Grill SW.Phys Rev Lett2011https://doi.org/10.1103/PhysRevLett.106.028103
Measuring the complete force field of an optical trapJahnel M, Behrndt M, Jannasch A, Schäffer E, Grill SW.Opt Lett2011https://doi.org/10.1364/OL.36.001260
PAR proteins diffuse freely across the anterior-posterior boundary in polarized C. elegans embryosGoehring NW, Hoege C, Grill SW, Hyman AA.J Cell Biol2011https://doi.org/10.1083/jcb.201011094
Polarization of PAR proteins by advective triggering of a pattern-forming systemGoehring NW, Trong PK, Bois JS, Chowdhury D, Nicola EM, Hyman AA, Grill SW.Science2011https://doi.org/10.1126/science.1208619
FRAP analysis of membrane-associated proteins: lateral diffusion and membrane-cytoplasmic exchangeGoehring NW, Chowdhury D, Hyman AA, Grill SW.Biophys J2010https://doi.org/10.1016/j.bpj.2010.08.033
Anisotropies in cortical tension reveal the physical basis of polarizing cortical flowsMayer M, Depken M, Bois JS, Jülicher F, Grill SW.Nature2010https://doi.org/10.1038/nature09376
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