The Brugués group has a strong background in biophysics, combining both theory and experiments. From the experimental side the Brugués lab uses cytoplasmic extracts, in vivo measurements and in vitro reconstitution. Key research topics have included co-condensation of DNA and protein interactions^1,2, methods to quantitatively measure protein concentration in condensates³, reconstitution of chromatin processes in single DNA strands⁴, and self-organization and mechanics of the mitotic spindle as an active liquid droplet^5-8. In recent years, the group has developed a theoretical framework for polymers in mixed solvents which explaining unusual phase transition scenarios. In collaboration with the Alberti and Jahnel groups, we have demonstrated that capillary-like forces arising from DNA-protein interactions play a key role in DNA damage².