26.10.2026
New Study – In vitro binding energies capture Klf4 occupancy across the human genome
While transcription factors (TFs) bind genomic DNA at specific positions to control gene expression, it is unclear which parameters dictate the low-affinity binding of TFs to non-motif sequences despite their importance. Can we develop a model to robustly predict transcription factor binding on…
30.11.2022
Molecular Assembly Lines in Active Droplets
Cells assemble structures that have lots of molecules. How can such complicated structures be reliably assembled? We propose that cells could be organizing an assembly line process for the construction. We show how this could be organized inside droplets. In this video we explain our recent…
30.11.2022
A quick intro to the Phase Diagram
Phase Diagrams are graphic representations that help understand many physical systems such as magnets and pure substances like water. These diagrams also help us understand how dense droplets of biomolecules, called Biomolecular Condensates, form inside cells. Phase Diagrams predict under which…