Research Focus
Biological membranes are fascinating composites of lipids, proteins and sugars. Our aim is to understand how the molecular components self-organize into meso-scale complexes that control processes as adhesion, polarization, signaling / sensing, which underlie morphogenesis of cells and tissues.
Alf Honigmann Group
Membrane Organization of Cells and Tissues
Research Group Leader: Alf Honigmann
Discipline: Biophysics
Affiliation: Biotec (TU-Dresden)
Contact: alf.honigmann@tu-dresden.de
Research Group Website: Alf Honigmann Group
Join the group through: DIGS-BB
Current news by this research group
Simon Alberti Group,Alf Honigmann Group,Anthony Hyman Group,Marcus Jahnel Group
A role for RNA in Stress Granules assembly
Stress granules are membraneless compartments formed by phase separation of specific molecules upon exposure to cellular stress such as oxidative stress, heat shock, or osmotic stress. The Alberti, Jahnel, Honigmann, and Hyman labs published a study in cell highlighting the role of RNA in the…
Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells
Aminoacyl-tRNA synthetases (aaRSs), the enzymes responsible for coupling tRNAs to their cognate amino acids, minimize translational errors by intrinsic hydrolytic editing. Here, we compared norvaline (Nva), a linear amino acid not coded for protein synthesis, to the proteinogenic, branched valine…
Moritz Kreysing Group,Simon Alberti Group,Anthony Hyman Group
Condensation regulates translation
New insights into the influence of Ded1p condensation on translation comes from the Hyman, Alberti and Kreysing labs. The study published in Cell is entitled "Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production". Graphical abstract: Abstract: Cells…
Alberti Lab is accepting applications for MSc, PhD, and Postdoc
We are always looking for highly motivated and creative students. Students interested in a master’s project with a focus on biochemistry, biophysics or cell biology are encouraged to apply. Students interested in a PhD project should apply to the Dresden International Graduate School for…
Simon Alberti Group,Stefan Diez Group,Anthony Hyman Group,Marcus Jahnel Group
Local nucleation of microtubule bundles through tubulin concentration into a condensed tau phase
Theskeleton that supports the structure of our cells, termed cytoskeleton is formed of several kinds of polymers including actin and microtubules. How the single units on the polymers (monomers and dimers) are concentrated to gether to synthesize the polymer is the subject of this study by the labs…
