30. November 2022
Molecular Assembly Lines in Active Droplets
Cells assemble structures that have lots of molecules. How can such complicated structures be reliably assembled? We propose that cells could be organizing an assembly line process for the construction. We show how this could be organized inside droplets. In this video we explain our recent…
23. May 2022
Join us as a Masters or PhD student: Chemical reactions in lattice polymer models
Required experience in the following methods: Statistical physics, molecular dynamics, monte carlo, lattice simulations Work with: Dr. Tyler Harmon | Tel: +49 (351) 4658 1216 | Email: TylerHarmon@ipfdd.de Prof. Dr. Jens-Uwe Sommer | Tel: +49 (351) 4658 750 | Email: Sommer@ipfdd.de……
23. May 2022
Join us as a Masters or PhD student: Surfactants stabilizing surfaces of cellular droplets
Required experience in the following methods: Statistical physics, molecular dynamics, monte carlo, lattice simulations Work with: Dr. Tyler Harmon | Tel: +49 (351) 4658 1216 | Email: TylerHarmon@ipfdd.de Prof. Dr. Jens-Uwe Sommer | Tel: +49 (351) 4658 750 | Email: Sommer@ipfdd.de……
23. May 2022
Join us as a Masters or PhD student: Mechanisms for storing memory in cellular droplets
Required experience in the following methods: statistical physics, 3D reaction diffusion models, critical behavior around bifurcations Work with: Dr. Tyler Harmon | Tel: +49 (351) 4658 1216 | Email: TylerHarmon@ipfdd.de Prof. Dr. Jens-Uwe Sommer | Tel: +49 (351) 4658 750 | Email:…
18. February 2022
New Study: A multi-step nucleation process determines the kinetics of prion-like domain phase separation
In this study, time-resolved small-angle X-ray scattering (SAXS) was used to characterize liquid-liquid phase separation of Prion-like domains. Read more
19. September 2023
A quick intro to the Physics of Wetting
Water forms droplets on the surface of a leaf but it spreads and completely wets the skin of a snail. Why does water behave so differently on the two surfaces? In this video, we introduce the fundamental concepts of surface tension, contact angle and the difference between hydrophobic and…
8. August 2023
How Protein Condensates Age
Protein condensates are dense droplets of proteins that organise the interior of the cell. Curiously, they age, meaning their physical properties such as viscosity change over time. In our paper "Theory of rheology and aging of protein condensates" published in PRX Life, we study how…
31. May 2023
Diving into the Free Energy: Part 1
Get ready to dive into the Free Energy! Cells can be described as systems made of different phases. For instance, biomolecular condensates are dense droplets of proteins that coexist with the rest of the cytoplasm. Thermodynamics is a helpful theoretical framework to understand phases in…
31. May 2023
Diving into the Free Energy: Part 2
Get ready to dive into the Free Energy! If we want to understand phases in cells we need to talk about the Free Energy of a thermodynamic system. This is the second part of the video “Diving into the Free Energy”. In this video, we will understand how thermodynamic mixtures reach…
6. April 2023
CD-Code is now published in Nature Methods
CD-CODE is now published in Nature Methods. It is a “living database” that we designed for fast addition and review of information about condensates and proteins and is open to users and expert researchers who would like to contribute. Join us and visit cd-code! CD code has been a…