Cytoskeletal organization through multivalent interactions

Stefan Diez and collaborators Zdenek Lansky and Marcus Braun from the Institute of Biotechnology of the Czech Academy of Sciences, Czech Republic, published an Opinion article emphasizing the role of multivalent interactions cytoskeletal phenomena including (1) the generation of entropic forces by filament crosslinkers, (2) processivity of molecular motors, (3) spatial sorting of proteins, and (4) concentration-dependent unbinding of filament-associated proteins. The article was published in the Journal of Cell Science.

Consequences of multivalent interactions on ligand–receptor interaction kinetics