Research Focus

In order for the cell to function properly, proteins must be robust to both changes in their environment and errors made during their synthesis. At the same time, proteins also need to be able to evolve novel functions to survive on long evolutionary timescales. The very same processes, i.e. genetic and phenotypic mutations, generate the diversity that leads to functional innovations and broken proteins, ultimately resulting in novel organisms, diseases and in some cases extinction.
In short, proteins exhibit evolutionary plasticity. But how do proteins remain robust and facilitate innovations at the same time? How can we distinguish variations, genetic and phenotypic, that are good or bad?

Current news by this research group

Condensation regulates translation

New insights into the influence of Ded1p condensation on translation comes from the Hyman, Alberti and Kreysing labs. The study published in Cell is entitled "Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production". Graphical abstract: Abstract: Cells…

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Postdoc (m/f/d)

Project Title Origin-of-cellular-Life’ / Out-of-equilibrium biophysical Systems Brief summary Our lab pursues experimental biophysical research. We are interested in the spatiotemporal patterning of living and chemical systems. The lab investigates how the spatial organization of molecules can…

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