CD-Code is now published in Nature Methods

CD-CODE is now published in Nature Methods. It is a “living database” that we designed for fast addition and review of information about condensates and proteins and is open to users and expert researchers who would like to contribute. Join us and visit cd-code! CD code has been a…

A quick intro to the Phase Diagram

Phase Diagrams are graphic representations that help understand many physical systems such as magnets and pure substances like water. These diagrams also help us understand how dense droplets of biomolecules, called Biomolecular Condensates, form inside cells. Phase Diagrams predict under which…

Join us as a Postdoc to develop Smart Optical Tweezers to Probe Biomolecular Condensates

The Marcus Jahnel group for Dynamics of Biomolecules at the Cluster of Excellence "Physics of Life" and BIOTEC center, TU Dresden, are recruiting a Research Associate / Postdoc (m/f/x) to study RNA folding and RNA looping in biomolecular condensates. For more details and instructions to apply,…

Join us as a Postdoc to study RNA Biology in Biomolecular Condensates

The Marcus Jahnel group for Dynamics of Biomolecules at the Cluster of Excellence "Physics of Life" and BIOTEC center, TU Dresden, are recruiting a Research Associate / Postdoc (m/f/x) to start immediately to study RNA folding and RNA looping in biomolecular condensates. For more details and…

Physics of Life Excellence Postdoctoral Fellowships

Join research groups at the Physics of Life (PoL) as a postdoc by applying to a PoL Excellence Postdoctoral Fellowship and benefit from up to 4-year funded position in association with PoL groups and the Mentorship program. Applicants should hold a PhD in Physics, Biology or related fields (at the…

A role for RNA in Stress Granules assembly

Stress granules are membraneless compartments formed by phase separation of specific molecules upon exposure to cellular stress such as oxidative stress, heat shock, or osmotic stress. The Alberti, Jahnel, Honigmann, and Hyman labs published a study in cell highlighting the role of RNA in the…

Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells

Aminoacyl-tRNA synthetases (aaRSs), the enzymes responsible for coupling tRNAs to their cognate amino acids, minimize translational errors by intrinsic hydrolytic editing. Here, we compared norvaline (Nva), a linear amino acid not coded for protein synthesis, to the proteinogenic, branched valine…

Condensation regulates translation

New insights into the influence of Ded1p condensation on translation comes from the Hyman, Alberti and Kreysing labs. The study published in Cell is entitled "Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production". Graphical abstract: Abstract: Cells…

The ALS-Associated FUS (P525L) Variant Does Not Directly Interfere with Microtubule-Dependent Kinesin-1 Motility

The Diez lab, in collaboration with the Hermann lab in Rostock, Germany, have utilised an in vitro microtubule gliding motility assay to study deficient intracellular transport in motor neurons. The findings  exclude a role of mutations in the phase-separating FUS protein, known to be mutated in…

Alberti Lab is accepting applications for MSc, PhD, and Postdoc

We are always looking for highly motivated and creative students. Students interested in a master’s project with a focus on biochemistry, biophysics or cell biology are encouraged to apply. Students interested in a PhD project should apply to the Dresden International Graduate School for…